GHK-Cu is a peptide, which is basically a chain of amino acids. Amino acids are the building blocks of protein, so peptides are sort of like shorter proteins. This peptide is made up of three amino acids: Glycine, Histidine, and Lysine (GHK).
GHK-Cu occurs naturally in the human body. It is most commonly found in the plasma of the blood. While it occurs in all of us, it tends to decline with age. In healthy 20 years olds, you will usually see levels of GHK-Cu at about 200 ng/ml in your blood plasma. By the time you reach 60, your GHK-Cu declines to an average of about 80 ng/ml.
Supplementing GHK-Cu can be a great way to increase your body’s ability to regenerate itself the way it could when you were younger.
Each of your cells has a copy of your genes. These are basically the blueprint to help your cells duplicate and create new cells. With age, the DNA gets damaged and changed so they express themselves differently. GHK-Cu’s job to prevent and reverse some of
this damage.
Some studies have found that this peptide can change how genes are expressed and can reverse expression to their healthier state. That basically means that the cells are able to repair themselves and duplicate better.
Because of its properties, GHK-Cu is typically used as a tissue regeneration agent. It has been found to help repair tissue damage, ulcers, lungs, and it may even help to regenerate nerves.
It also has some properties that make it a potent anti–aging agent. GHK-Cu has been shown to significantly reduce wrinkles in the skin and increase collagen formation. As a result, the skin becomes more elastic and it reduces its aging appearance.
GHK-Cu Benefits and Uses:
Here’s a relatively comprehensive list of all the different effects that GHK-Cu can have. Each of these come directly from scientific studies.
Skin repair
GHK-Cu’s most well-known effects are in skin and wound repair. A ton of animal studies have found that this copper peptide facilitates wound healing. It does that by elevating levels of antioxidant enzymes, contracting wounds, and speeding up tissue growth. It seems to do this effectively both as a topical ointment as well as through GHK-Cu injections..
Basically, if you’re looking to heal a wound quickly and effectively, GHK-Cu is a great option.
Anti-aging
One of the more promising uses of GHK-Cu is actually in cosmetics. It seems to have powerful anti-aging effects, including the substantial reduction of wrinkles and fine lines on the skin as well as increasing skin firmness and elasticity. There have been several high-quality controlled experiments using copper tripeptide in creams applied to the skin.
One study of women found that copper peptide was better than vitamin C and retinoic acid in increasing collagen and reducing fine lines and wrinkles.
In another study, researchers looked at the effects of GHK-Cu cream on 67 women over 12 weeks. They found that it was very effective at reducing wrinkles and increasing skin thickness. They also found that it was nontoxic and non-irritating.
It’s now a very well-known anti-aging agent and can be commonly found in skincare products.
Tissue Remodeling
There seems to be some evidence that it plays a role in remodeling tissue. This means it helps repair damaged tissue, including creating protein synthesis of collagen. Some studies have also found that there is an effect on the repair of lung tissue and also in tissue in the digestive system.
Hair growth
Heads up guys: copper tripeptide has been found to be effective in treating hair loss, including male-pattern baldness. In clinical trials, researchers found that it has performed as well as other well-recognized treatment options like Minoxidil. It can be used on thinning hair as well, stimulating growth and improving the strength of the hair that’s already there.
Anti-tumor and cancer
GHK-Cu has also been found to stimulate the creation of decorin, which is an important component not only in the formation of collagen but also in the defense against cancerous tumors.
Another study also found that copper tripeptide changed the expression of some genes that are involved in the formation and spread of colon cancer meaning it could be effective as a preventative measure.
More research is needed, but there are definitely some promising anti-cancer effects of GHK-Cu.
Nerve regeneration
While the science is not yet settled on all the effects of this copper tripeptide, it looks like it could be used to help nerve regeneration. One study found that GHK-Cu was involved in a number of processes that improve nerve regeneration. For example, it stimulated the production of nerve growth factors, increased axon count in nerve cells, and increased the proliferation of Schwann cells. Again, more evidence is needed to be sure, but there seem to be some promising findings of GHK-Cu in the regeneration of nerve tissue.
Anti-Pain, Anti-Anxiety, Anti-Aggression
Research on animals has also suggested that GHK-Cu reduces anxiety, improves tolerance to pain, and reduces aggression.
GHK-Cu Side Effects
What about the side effects? The benefits are great, but you want to make sure you’re not taking anything unsafe.
In general, this peptide is considered very safe. One of the likely reasons that it’s not toxic is that it already occurs naturally in your body. It’s not a foreign substance.
GHK-Cu Creams
As a cream, copper tripeptide seems to be virtually side-effect free. Some studies have concluded that it is non-toxic and also doesn’t irritate the skin. Applying creams topically has not been found to have any side-effects.
GHK-Cu Injections
One side effect mentioned by users is that it can sting when administered via injection. Another side effect is that GHK-Cu peptide can lower blood pressure. That means that you shouldn’t take too much at once.
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